Faili:Serpin mechanism.png

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Maelezo
English: Serine proteases operate by a two-step catalytic mechanism. First, the substrate (blue) is attacked by the catalytic triad (red) to form an acyl-enzyme intermediate. The intermediate is typically resolved by hydrolysis by water. However, when the reactive centre loop (RCL) of a serpin is attacked, the conformational change (blue arrow) pulls the catalytic triad out of position, preventing it from completing catalysis. (Based on PDB: 1K9O, 1EZX​)
Tarehe
Chanzo Kazi yangu
Mwandishi Thomas Shafee

Hatimiliki

I, the copyright holder of this work, hereby publish it under the following license:
w:en:Creative Commons
sifa
This file is licensed under the Creative Commons Attribution 4.0 International license.
Uko huru:
  • kushiriki – kunakili na kusambaza kazi hiyo
  • kwa remix – kurekebisha kazi
Chini ya masharti yafuatayo:
  • sifa – Ni lazima utoe mkopo unaofaa, utoe kiungo cha leseni, na uonyeshe ikiwa mabadiliko yalifanywa. Unaweza kufanya hivyo kwa njia yoyote inayofaa, lakini si kwa njia yoyote inayopendekeza mtoa leseni akuidhinishe wewe au matumizi yako.

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depicts Kiingereza

copyright status Kiingereza

copyrighted Kiingereza

19 Desemba 2015

media type Kiingereza

image/png

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Tarehe/SaaPicha ndogoVipimoMtumiajiMaelezo
sasa hivi09:56, 22 Desemba 2015Picha ndogo ya toleo la 09:56, 22 Desemba 20151,800 × 1,488 (513 KB)Evolution and evolvabilityHigher resolution
05:19, 19 Desemba 2015Picha ndogo ya toleo la 05:19, 19 Desemba 20151,362 × 1,126 (300 KB)Evolution and evolvabilityMinor arrow correction
05:08, 19 Desemba 2015Picha ndogo ya toleo la 05:08, 19 Desemba 20151,362 × 1,126 (300 KB)Evolution and evolvabilityadded arrow and removed transparency
05:04, 19 Desemba 2015Picha ndogo ya toleo la 05:04, 19 Desemba 20151,362 × 1,114 (360 KB)Evolution and evolvabilityCross-wiki upload from en.wikipedia.org

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