Kifua kikuu : Tofauti kati ya masahihisho

[[Nucleic asidi amplification mithani ]] na kupita [[ Triphosphate deaminase]] huweza kuruhusu uchunguzi wa haraka wa TB.<ref name=DiagP2011/> Vipimo hivi, hata hivyo, si mara kwa mara ilipendekeza, kama wao mara chache kubadilisha jinsi mtu ni kutibiwa.<ref name=NICE2011/> Vipimo vya damu ili kuchunguza kingamwili siyo maalum au nyeti [[ kingamwili siyo maalum au nyeti ]] na [[ unyeti na maalum au nyeti ]], hivyo si ilipendekeza.<ref>{{cite journal|last=Steingart|first=KR|coauthors=Flores, LL, Dendukuri, N, Schiller, I, Laal, S, Ramsay, A, Hopewell, PC, Pai, M|title=Commercial serological tests for the diagnosis of active pulmonary and extrapulmonary tuberculosis: an updated systematic review and meta-analysis.|journal=PLoS medicine|date=2011 Aug|volume=8|issue=8|pages=e1001062|pmid=21857806|doi=10.1371/journal.pmed.1001062|pmc=3153457}}</ref>

 

[[File:Mantoux tuberculin skin test .jpg thumb|[[Mantoux test|Mantoux tuberculin skin test]]]] [[Mantoux mithani |Mantoux tuberculin ngozi mithani mara nyingi hutumika kwa watu screen katika hatari kubwa ya TB.<ref name=Clinic2009/> Wale ambao wamekuwa awali chanjo wanaweza kuwa na uongo chanya mtihani matokeo.<ref name=Rothel_2005>{{cite journal author=Rothel J, Andersen P |title=Diagnosis of latent ''Mycobacterium tuberculosis'' infection: is the demise of the Mantoux test imminent?|journal=Expert Rev Anti Infect Ther |volume=3 |issue=6 |pages=981–93 |year=2005|pmid = 16307510|doi = 10.1586/14787210.3.6.981}}</ref>mtihani inaweza kuwa uongo hasi katika wale walio na [[sarcoidosis]], [[Hodgkin's lymphoma]], na [[utapiamlo]]. au wengi hasa, katika wale ambao kweli kufanya wana kifua kikuu hai.<ref name=Robbins/> [[Interferon assays katika vivuli mbalimbali ya njano lioenea, kuashiria juu ya watu 300 kwa kila 100,000, na kwa Marekani, Canada, Australia, na Ulaya ya kaskazini katika vivuli ya bluu kirefu, kuashiria kiwango cha maambukizi karibu 10 kwa kila watu 100,000. Asia ni njano lakini si hivyo kabisa mkali, kuashiria kiwango cha maambukizi ya kuzunguka 200 per mbalimbali 100,000. Amerika ya Kusini ni ya njano nyeusi. Mwaka 2007, kiwango cha maambukizi ya TB kwa watu 100,000 ilikuwa ya juu katika Afrika Kusini mwa Sahara, na pia alikuwa kiasi katika Asia.<ref>{{cite book |title=Global tuberculosis control: epidemiology, strategy, financing |author=World Health Organization |year=2009 |isbn=978-92-4-156380-2|chapter=The Stop TB Strategy, case reports, treatment outcomes and estimates of TB burden|chapterurl=http://who.int/tb/publications/global_report/2009/annex_3/en/index.html|accessdate=14 November 2009|pages=187–300}}</ref>[[ kutolewa gamma ]] (IGRAs) juu ya sampuli ya damu, ni ilipendekeza kwa wale ambao ni chanya kwa mtihani Mantoux.<refname=NICE2011>{{NICE|117|Tuberculosis|2011}}</ref> IGRAs Haya si walioathirika na chanjo au zaidi [[mazingira mycobacteria]], hivyo wao kuzalisha wachache [[matokeo ya uongo]] na HIV. <ref>{{cite journal|author=Pai M, Zwerling A, Menzies D|title=Systematic Review: T-Cell–based Assays for the Diagnosis of Latent Tuberculosis Infection: An Update |journal=Ann. Intern. Med. |volume=149 |issue=3 |pages=1–9 |year=2008 |pmid=18593687 |pmc=2951987}} </ref> hivyo wao kuzalisha wachache matokeo ya uongo na HIV. Hata hivyo wao walioathirika na M. szulgai, M. marinum na M. kansasii.”<ref>{{cite book|last=Jindal|first=editor-in-chief SK|title=Textbook of pulmonary and critical care medicine|publisher=Jaypee Brothers Medical Publishers|location=New Delhi|isbn=978-93-5025-073-0|pages=544|url=http://books.google.ca/books?id=rAT1bdnDakAC&pg=PA544}}</ref> IGRAs inaweza kuongeza usikivu wakati kutumika kwa kuongeza mtihani ngozi lakini inaweza kuwa chini zaidi kuliko mtihani nyeti ngozi wakati kutumika peke yake.<ref>{{cite journal|last=Amicosante|first=M|coauthors=Ciccozzi, M, Markova, R|title=Rational use of immunodiagnostic tools for tuberculosis infection: guidelines and cost effectiveness studies.|journal=The new microbiologica|date=2010Apr|volume=33|issue=2|pages=93107|pmid=205181}}</ref>.